In relation to fantasy football injuries, Week 2 of the 2020 NFL season will go down as one of the most catastrophic in recent fantasy football history. Saquon Barkley and Christian McCaffrey , the presumptive number one and number two overall picks in preseason drafts, went down with injuries (Barkley’s is season ending). Fantasy players also will have to navigate Week 3 without two big pieces of the 49ers backfield as well. In short, Week 2 proved that you can never roster too many fantasy RBs.

The following is an in-depth look at how some specific teams have managed their backfields thus far this season. We’ve also included analysis’ of how the Giants, Panthers and 49ers backfields might be structured moving forward in post-apocalyptic Week 3 in the NFL.  We hope that the following will help you to better manage your fantasy football team(s).

Carolina Panthers

While he’s telling anyone who will listen that he’ll be back sooner, Christian McCaffrey is expected to miss...