The differences in scoring for EPL DFS between DraftKings and FanDuel is probably more drastic than for any other sport. DraftKings rewards crosses a ton, while FanDuel doles out a lot of points for clearances and chances created. For that reason, I feel like I have a separate list of players for each site. There is obviously some overlap, mostly among goal-scorers and goal keepers, but often I’ll use several players on one site I wouldn’t even consider on the other.

Saturday’s slate, for whatever reason, is different. There are several players I like quite a bit on both sites, including a couple of defenders. I’ll still try to diversify my lineups a fair amount, but it’s nice to know I can use someone like Antonee Robinson with confidence on either site.

Goal Keepers
PlayerTeamOpp.DK $DK FPPGFD $FD FPPG
Karl DarlowNEWFUL49008.471012.96
I'm still not comfortable paying up for Karl Darlow, but Fulham has scored the fewest goals (five) of any team on the slate over the last six gameweeks, and Newcastle are slightly favored at home. 
Bernd LenoARSEVE4500699.00
Everton have eight goals on 32 shots in their last six games, while Arsenal have conceded nine goals in that same span despite repeatedly going down a man. If Leno's teammates can refrain from doing something stupid, which is admittedly a huge "if", Leno could easily be the best value on the slate. It should also help Leno that James Rodriguez is out.
Forwards
PlayerTeamOpp.DK $DK FPPGFD $FD FPPG
Pierre-Emerick AubameyangARSEVE70008.831913.12
Aubameyang finally scored (in the correct goal) on Wednesday. Everton's defense has been better but it still isn't good, and Aubameyang has a decent shot at a goal at a reasonable price.
Ademola LookmanFULNEW770011.361718.60
Bobby De Cordova-Reid may have the most goals for Fulham, but Lookman is first in shots on target and chances created and second in shots and goals. He is the safest of the Fulham attackers.
Aboubakar KamaraFULNEW35001.8372.24
Kamara has 4.18 crosses per 90 minutes this season, and he will likely take Bobby De Cordova-Reid's spot on the wing. I don't expect him to be as good as De Cordova-Reid has been, but he doesn't have to be at his price.
Callum WilsonNEWFUL810013.171820.47
Newcastle's attackers have the best matchup on the slate, but while they have multiple players who are capable of created chances, Wilson is the only player I trust to finish them.
Midfielders
PlayerTeamOpp.DK $DK FPPGFD $FD FPPG
Bukayo SakaARSEVE750010.651111.07
Saka was disappointing against Southampton, but he still had five crosses, a chance created and a shot on goal. I think Arsenal's attack will be back on track to some degree against Everton, which would give Saka a high ceiling in addition to the high floor.
Gylfi SigurdssonEVEARS71007.291410.08
I have been burned by trusting Sigurdsson before, but it's hard not to trust him when he has 13 crosses and nine chances created in two games with James Rodriguez out. Sigiurdsson is on penalties as well, which makes him playable in all formats.
Ryan FraserNEWFUL66006.26115.45
We're no longer getting him at a huge discount like we were Wednesday, but he is still $1400 cheaper than Matt Ritchie. Fraser and Ritchie should share set pieces, and only three teams have conceded more goals than Fulham this season.
Ilkay GundoganMCISOU61007.881210.40
It looks like we finally have another safe City asset, as Gundogan is averaging 10.74 DK fantasy points in five starts this season. I like him even better on FanDuel, where his nine chances created have more value.
Kevin De BruyneMCISOU1110020.282424.55
I'm not sure what is left to say about De Bruyne at this point. He had five chances created and 16 crosses against West Brom Tuesday.
MidfieldersTeamOpp.DK $DK FPPGFD $FD FPPG
Moussa DjenepoSOUMCI31004.5597.48
He has been consistent on both sites, with four chances created and four shots in his last four starts.
Riyad MahrezMCISOU910015.141822.52
I don't know why he is so cheap on FanDuel. He has slowed down a bit after a very nice stretch, but I still think he's the city attacker I trust the most outside of Kevin De Bruyne.
Defenders
PlayerTeamOpp.DK $DK FPPGFD $FD FPPG
Hector BellerinARSEVE39005.9911.22
Bellerin was very disappointing against Burnley, but he still has 20 crosses in his last six games. I think he is clearly safer for DFS than any of the other defenders in his price range. If Bellerin doesn't get the start, Ainsley Maitland-Niles would be a cheaper alternative.
Seamus ColemanEVEARS44006.72912.10
Coleman has at least 6.6 DK fantasy points in every game he has played at least 35 minutes. He is safer than Bellerin, but not much more expensive. 
Antonee RobinsonFULNEW50007.481315.95
Newcastle have the fewest touches in the Premier League, and Robinson should get plenty of chances to get forward. He has three crosses in each of his last two games, with three chances created in that span. He looks safe on both sites.
Michael KeaneEVEARS31005.461414.28
Keane is averaging 17.4 FD fantasy points in his last four games. So long as Everton continues to play a back three, Keane is as safe as it gets.
Yerry MinaEVEARS28005.071114.14
Like Keane, Mina has been good since going to a back three, but his price hasn't gone up nearly as much.

As always, the lineups below are examples of lineups you can make using the players in the Playbook and are not for plug and play.

DK CashPivotDK Cash Pivot
Pos.PlayerTeamOppFPPGSalary Pos.PlayerTeamOppFPPGSalary
FBukayo SakaARSEVE10.65$7,500 F     
FAboubakar KamaraFULNEW1.83$3,500ToFBobby Cordova-ReidFULNEW6.73$5,500
MGylfi SigurdssonEVEARS7.29$7,100ToMIlkay Gundogan MCI SOU7.88$6,100
MKevin De BruyneMCISOU20.28$11,100 M     
DSeamus ColemanEVEARS6.72$4,400 D     
DHector BellerinARSEVE5.9$3,900 D     
GKBernd LenoARSEVE6$4,500 GK     
UtilMatt RitchieNEWFUL8.71$8,000ToUtilRyan FraserNEWFUL6.26$6,600
    Total$50,000     Total$18,200
             
DK GPPPivotDK Pivot GPP
Pos.PlayerTeamOppFPPGSalary Pos.PlayerTeamOppFPPGSalary
FCallum WilsonNEWFUL13.17$8,100 F     
FAdemola LookmanFULNEW11.36$7,700 F     
MMoussa DjenepoSOUMCI4.55$3,100 M     
MRiyad MahrezMCISOU15.14$9,100ToMRaheem SterlingMCISOU10.33$9,400
DSeamus ColemanEVEARS6.72$4,400 D     
DAntonee RobinsonFULNEW7.48$5,000 D     
GKKarl DarlowNEWFUL8.47$4,900 GK     
UtilGylfi SigurdssonEVEARS7.29$7,100ToUtilDominic Calvert-LewinEVEARS15.6$7,400
    Total$49,400     Total$16,800
             
FD CashPivotFD Cash Pivot
PosPlayerTeamOppFPPGSalary PosPlayerTeamOppFPPGSalary
F/MMoussa DjenepoSOUMCI7.48$9 F/M     
F/MKevin De BruyneMCISOU24.55$24 F/M     
F/MAdemola LookmanFULNEW18.60$17 F/M     
F/MGylfi SigurdssonEVEARS10.08$14ToF/MPhil FodenMCISOU10.62$14
DMichael KeaneEVEARS14.28$14 D     
DAntonee RobinsonFULNEW15.95$13ToDJan BednarekSOUMCI14.32$13
GKBernd LenoARSEVE9.00$9 GK     
    Total$100     Total$27
             
FD GPPPivotFD Pivot GPP
PosPlayerTeamOppFPPGSalary PosPlayerTeamOppFPPGSalary
F/MCallum WilsonNEWFUL20.47$18 F/M     
F/MRiyad MahrezMCISOU22.52$18 F/M     
F/MAdemola LookmanFULNEW18.60$17To F/MBobby De Cordova-ReidFULNEW12.10$15
F/MDanny IngsSOUMCI22.38$17To F/MPierre-Emerick AubameyangARSEVE13.12$19
DSeamus ColemanEVEARS12.10$9 D     
DYerry MinaEVEARS14.14$11 D     
GKKarl DarlowNEWFUL12.96$10 GK     
    Total$100     Total$34